Logistics network is a spatial structure composed of nodes and links. Nodes is the core of this network, and through factor analysis and cluster analysis, we can clarify the hierarchical structure of nodes. However, as to the nodes on the same layer, their coverage region hasn't been clearly classified, which restricts the development of regional logistics taking single node as the center. TakingJinan, one of the 21 logistics nodes all over the country, as an example, through factor analysis, we can have a clear idea about the comprehensive strength of logistics nodes and through cluster analysis, we can find the hierarchical structure of logistics nodes. The main goal of selecting logistic operation is to minimize the cost, to balance the cost of logistics, and to clarify the demarcation point of nodes in the same layer. The research result has realistic guiding significance to the function orientation of regional logistics center and market orientation of logistic enterprise in this area.